Reorganization of the Human Somatosensory Cortex in Hand Dystonia
نویسندگان
چکیده
BACKGROUND AND PURPOSE Abnormalities of finger representations in the somatosensory cortex have been identified in patients with focal hand dystonia. Measuring blood flow with positron emission tomography (PET) can be use to demonstrate functional localization of receptive fields. METHODS A vibratory stimulus was applied to the right thumb and little finger of six healthy volunteers and six patients with focal hand dystonia to map their receptive fields using H2 (15)O PET. RESULTS The cortical finger representations in the primary somatosensory cortex were closer to each other in patients than in normal subjects. No abnormalities were found in secondary somatosensory cortex, but the somatotopy there is less well distinguished. CONCLUSIONS These data confirm prior electrophysiological and functional neuroimaging observations showing abnormalities of finger representations in somatosensory cortex of patients with focal hand dystonia.
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A Combination of Constraint-induced Therapy and Motor Control Retraining in the Treatment of Focal Hand Dystonia in Musicians – a Long-term Follow-up Study
Purpose and relevance Focal hand dystonia (FHD) in musicians is a painless task-specific motor disorder characterized by involuntary loss of control of individual finger movements. It is associated with decreased cortical inhibition, and maladaptive cortical reorganization showing fusion of the representational zones of the digits in the primary somatosensory cortex. Research investigating the ...
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